Ingrid Holm

Ingrid Holm, MD, MPH

Attending Physician, Division of Endocrinology; Attending Physician, Division of Genetics and Genomics
Professor of Pediatrics, Harvard Medical School
Member, HMS Center for Bioethics
BCH Division of Genetics and Genomics, 3 Blackfan Circle, Boston, MA 02115

Ingrid A. Holm, MD, MPH is Professor of Pediatrics at Harvard Medical School, faculty in the Division of Genetics and Genomics at Boston Children's Hospital, and teaching faculty at the HMS Center for Bioethics. She is a medical geneticist by training, and she has a certificate in Pediatric Bioethics.

Dr. Holm's primary area of research is the Ethical, Legal, and Social Implications (ELSI) of genomics. She is co-PI of an NIH-funded grant to look at the implementation of genome sequencing as screening in a diverse cohort of healthy infants (BabySeq2). She is co-PI of an NHGRI grant to providing ethical guidance for the development of individualized genomic medicines as rare as n-of-1. She is a co-investigator in the NHGRI-funded Electronic Medical Records and Genomics (eMERGE) Network; a co-investigator at the Harvard Undiagnosed Diseases Network (UDN) site; and Associate Director of Robert's Program in Sudden Unexpected Death in Pediatrics (SUDP), which takes an innovative approach to SUDP as a group of rare genetic diseases. Dr. Holm is Chair of BCH IRB and a member of the NIH-funded All of Us (Precision Medicine Initiative) Research Program IRB.

Publications View
Advancing Understanding of Inequities in Rare Disease Genomics.
Authors: Authors: Serrano JG, O'Leary M, VanNoy G, Holm IA, Fraiman YS, Rehm HL, O'Donnell-Luria A, Wojcik MH.
medRxiv
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Copy Number Variation and Structural Genomic Findings in 116 Cases of Sudden Unexplained Death between 1 and 28 Months of Age.
Authors: Authors: Brownstein CA, Douard E, Haynes RL, Koh HY, Haghighi A, Keywan C, Martin B, Alexandrescu S, Haas EA, Vargas SO, Wojcik MH, Jacquemont S, Poduri AH, Goldstein RD, Holm IA.
Adv Genet (Hoboken)
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Parents' decision-making regarding whether to receive adult-onset only genetic findings for their children: Findings from the BabySeq Project.
Authors: Authors: Pereira S, Gutierrez AM, Robinson JO, Christensen KD, Genetti CA, Blout Zawatsky CL, Hsu RL, Zettler B, Uveges MK, Parad RB, Beggs AH, Holm IA, Green RC, McGuire AL.
Genet Med
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Genetic Predictors of Blood Pressure Traits are Associated with Preeclampsia.
Authors: Authors: Jasper EA, Hellwege JN, Breeyear JH, Xiao B, Jarvik GP, Stanaway IB, Leppig KA, Chittoor G, Hayes MG, Dikilitas O, Kullo IJ, Holm IA, Verma SS, Edwards TL, Velez Edwards DR.
medRxiv
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The fundamental need for unifying phenotypes in sudden unexpected pediatric deaths.
Authors: Authors: Wojcik MH, Poduri AH, Holm IA, MacRae CA, Goldstein RD.
Front Med (Lausanne)
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Re: Technical Report for Updated 2022 Recommendations for Reducing Infant Deaths in the Sleep Environment.
Authors: Authors: Holm IA, Poduri A, Goldstein RD.
Pediatrics
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Attitudes among Parents towards Return of Disease-Related Polygenic Risk Scores (PRS) for Their Children.
Authors: Authors: Terek S, Del Rosario MC, Hain HS, Connolly JJ, Behr MA, Harr M, Hakonarson H, Holm IA.
J Pers Med
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Outcomes of Returning Medically Actionable Genomic Results in Pediatric Research.
Authors: Authors: Blumling AA, Prows CA, Harr MH, Chung WK, Clayton EW, Holm IA, Wiesner GL, Connolly JJ, Harley JB, Hakonarson H, McGowan ML, Miller EM, Myers MF.
J Pers Med
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Impact of returning unsolicited genomic results to nongenetic health care providers in the eMERGE III Network.
Authors: Authors: Madden JA, Brothers KK, Williams JL, Myers MF, Leppig KA, Clayton EW, Wiesner GL, Holm IA.
Genet Med
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The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network.
Authors: Authors: Leppig KA, Kulchak Rahm A, Appelbaum P, Aufox S, Bland HT, Buchanan A, Christensen KD, Chung WK, Clayton EW, Crosslin D, Denny J, DeVange S, Gordon A, Green RC, Hakonarson H, Harr MH, Henrikson N, Hoell C, Holm IA, Kullo IJ, Jarvik GP, Lammers PE, Larson EB, Lindor NM, Marasa M, Myers MF, Perez E, Peterson JF, Pratap S, Prows CA, Ralston JD, Rasouly HM, Roden DM, Sharp RR, Singh R, Shaibi G, Smith ME, Sturm A, Thiese HA, Van Driest SL, Williams J, Williams MS, Wynn J, Blout Zawatsky CL, Wiesner GL.
Genet Med
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