Ingrid Holm

Ingrid Holm, MD, MPH

Attending Physician, Division of Endocrinology; Attending Physician, Division of Genetics and Genomics
Professor of Pediatrics, Harvard Medical School
Member, HMS Center for Bioethics
BCH Division of Genetics and Genomics, 3 Blackfan Circle, Boston, MA 02115

Ingrid A. Holm, MD, MPH is Professor of Pediatrics at Harvard Medical School, faculty in the Division of Genetics and Genomics at Boston Children's Hospital, and teaching faculty at the HMS Center for Bioethics. She is a medical geneticist by training, and she has a certificate in Pediatric Bioethics.

Dr. Holm's primary area of research is the Ethical, Legal, and Social Implications (ELSI) of genomics. She is co-PI of an NIH-funded grant to look at the implementation of genome sequencing as screening in a diverse cohort of healthy infants (BabySeq2). She is co-PI of an NHGRI grant to providing ethical guidance for the development of individualized genomic medicines as rare as n-of-1. She is a co-investigator in the NHGRI-funded Electronic Medical Records and Genomics (eMERGE) Network; a co-investigator at the Harvard Undiagnosed Diseases Network (UDN) site; and Associate Director of Robert's Program in Sudden Unexpected Death in Pediatrics (SUDP), which takes an innovative approach to SUDP as a group of rare genetic diseases. Dr. Holm is Chair of BCH IRB and a member of the NIH-funded All of Us (Precision Medicine Initiative) Research Program IRB.

Publications View
The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network.
Authors: Authors: Leppig KA, Kulchak Rahm A, Appelbaum P, Aufox S, Bland HT, Buchanan A, Christensen KD, Chung WK, Clayton EW, Crosslin D, Denny J, DeVange S, Gordon A, Green RC, Hakonarson H, Harr MH, Henrikson N, Hoell C, Holm IA, Kullo IJ, Jarvik GP, Lammers PE, Larson EB, Lindor NM, Marasa M, Myers MF, Perez E, Peterson JF, Pratap S, Prows CA, Ralston JD, Rasouly HM, Roden DM, Sharp RR, Singh R, Shaibi G, Smith ME, Sturm A, Thiese HA, Van Driest SL, Williams J, Williams MS, Wynn J, Blout Zawatsky CL, Wiesner GL.
Genet Med
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Genetic Determinants of Sudden Unexpected Death in Pediatrics.
Authors: Authors: Koh HY, Haghighi A, Keywan C, Alexandrescu S, Plews-Ogan E, Haas EA, Brownstein CA, Vargas SO, Haynes RL, Berry GT, Holm IA, Poduri AH, Goldstein RD.
Genet Med
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Do research participants share genomic screening results with family members?
Authors: Authors: Wynn J, Milo Rasouly H, Vasquez-Loarte T, Saami AM, Weiss R, Ziniel SI, Appelbaum PS, Wright Clayton E, Christensen KD, Fasel D, Green RC, Hain HS, Harr M, Hoell C, Kullo IJ, Leppig KA, Myers MF, Pacyna JE, Perez EF, Prows CA, Kulchak Rahm A, Campbell-Salome G, Sharp RR, Smith ME, Wiesner GL, Williams JL, Blout Zawatsky CL, Gharavi AG, Chung WK, Holm IA.
J Genet Couns
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Effects of participation in a U.S. trial of newborn genomic sequencing on parents at risk for depression.
Authors: Authors: Schwartz TS, Christensen KD, Uveges MK, Waisbren SE, McGuire AL, Pereira S, Robinson JO, Beggs AH, Green RC, Bachmann GA, Rabson AB, Holm IA.
J Genet Couns
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Population-Based Screening of Newborns: Findings From the NBS Expansion Study (Part One).
Authors: Authors: Brower A, Chan K, Williams M, Berry S, Currier R, Rinaldo P, Caggana M, Gaviglio A, Wilcox W, Steiner R, Holm IA, Taylor J, Orsini JJ, Brunelli L, Adelberg J, Bodamer O, Viall S, Scharfe C, Wasserstein M, Chen JY, Escolar M, Goldenberg A, Swoboda K, Ficicioglu C, Matern D, Lee R, Watson M.
Front Genet
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Parental Attitudes Toward Standard Newborn Screening and Newborn Genomic Sequencing: Findings From the BabySeq Study.
Authors: Authors: Armstrong B, Christensen KD, Genetti CA, Parad RB, Robinson JO, Blout Zawatsky CL, Zettler B, Beggs AH, Holm IA, Green RC, McGuire AL, Smith HS, Pereira S.
Front Genet
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Retrospective study of patterns of vitamin D testing and status at a single institution paediatric orthopaedics and sports clinics.
Authors: Authors: Mahan S, Ackerman K, DiFazio R, Miller P, Feldman L, Sullivan N, Glotzbecker M, Holm IA.
BMJ Open
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Current Trends in Genetics and Neonatal Care.
Authors: Authors: Uveges MK, Holm IA.
Adv Neonatal Care
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Psychosocial Effect of Newborn Genomic Sequencing on Families in the BabySeq Project: A Randomized Clinical Trial.
Authors: Authors: Pereira S, Smith HS, Frankel LA, Christensen KD, Islam R, Robinson JO, Genetti CA, Blout Zawatsky CL, Zettler B, Parad RB, Waisbren SE, Beggs AH, Green RC, Holm IA, McGuire AL.
JAMA Pediatr
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Association of Prenatal Exposure to Maternal Drinking and Smoking With the Risk of Stillbirth.
Authors: Authors: Odendaal H, Dukes KA, Elliott AJ, Willinger M, Sullivan LM, Tripp T, Groenewald C, Myers MM, Fifer WP, Angal J, Boyd TK, Burd L, Cotton JB, Folkerth RD, Hankins G, Haynes RL, Hoffman HJ, Jacobs PK, Petersen J, Pini N, Randall BB, Roberts DJ, Robinson F, Sens MA, Van Eerden P, Wright C, Holm IA, Kinney HC.
JAMA Netw Open
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