Willy Lensch

Willy Lensch, PhD

Lecturer on Global Health and Social Medicine, Part-time
Member, HMS Center for Bioethics
Richard A. and Susan F. Smith Campus Center

M. William Lensch, PhD, is Associate Provost for Research at Harvard University and a Lecturer (part-time) in the Department of Global Health and Social Medicine at Harvard Medical school (HMS)l. He received his PhD in Molecular and Medical Genetics from Oregon Health Sciences University where he studied hereditary bone marrow failure and leukemia predisposition syndromes at the Portland Veteran’s Administration Medical Center. Dr. Lensch is a past Fellow of the Center for Bioethics. His professional portfolio within the provost’s office spans the schools of Harvard and provides high level management/guidance for interfaculty research and educational initiatives (IFIs) in the physical, life, and social sciences. His work in bioethics includes issues related to rare diseases, genetic modification, use of human tissues in research, stem cell biology, human/animal chimeras, and the disposition of human remains in museum collections. Dr. Lensch has served in various external roles including as a gubernatorial appointee to the State of Connecticut’s Stem Cell Research Advisory Committee, a member of the Public Education Committee of the International Society for Stem Cell Research, and as Chair of the Bioethics Subcommittee of the national American Heart Association. His recognition includes multiple Certificates of Distinction in Teaching from Harvard’s Derek Bok Center for Teaching and Learning, the Staff Family Prize for Excellence in Student Advising, and HMS’s Daniel D. Federman Staff Award for Exceptional Service, the latter for his role in the founding, operation, and ongoing strategy of the Massachusetts Consortium on Pathogen Readiness (MassCPR) during the global COVID-19 pandemic.

Publications View
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction.
Authors: Authors: Tulpule A, Kelley JM, Lensch MW, McPherson J, Park IH, Hartung O, Nakamura T, Schlaeger TM, Shimamura A, Daley GQ.
Cell Stem Cell
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From stealing fire to cellular reprogramming: a scientific history leading to the 2012 Nobel Prize.
Authors: Authors: Lensch MW, Mummery CL.
Stem Cell Reports
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Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition.
Authors: Authors: Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ.
Proc Natl Acad Sci U S A
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An evolving model of hematopoietic stem cell functional identity.
Authors: Authors: Lensch MW.
Stem Cell Rev Rep
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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells.
Authors: Authors: Kim K, Zhao R, Doi A, Ng K, Unternaehrer J, Cahan P, Huo H, Loh YH, Aryee MJ, Lensch MW, Li H, Collins JJ, Feinberg AP, Daley GQ.
Nat Biotechnol
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Public perception of stem cell and genomics research.
Authors: Authors: Lensch MW.
Genome Med
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Investigating monogenic and complex diseases with pluripotent stem cells.
Authors: Authors: Zhu H, Lensch MW, Cahan P, Daley GQ.
Nat Rev Genet
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Reprogramming of T cells from human peripheral blood.
Authors: Authors: Loh YH, Hartung O, Li H, Guo C, Sahalie JM, Manos PD, Urbach A, Heffner GC, Grskovic M, Vigneault F, Lensch MW, Park IH, Agarwal S, Church GM, Collins JJ, Irion S, Daley GQ.
Cell Stem Cell
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Induced pluripotent stem cells: opportunities and challenges.
Authors: Authors: Lensch MW, Rao M.
Regen Med
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Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.
Authors: Authors: Tulpule A, Lensch MW, Miller JD, Austin K, D'Andrea A, Schlaeger TM, Shimamura A, Daley GQ.
Blood
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