Insoo Hyun
Insoo Hyun, Ph.D.
Director of Research Ethics
Senior Lecturer on Global Health and Social Medicine, Part-time, Harvard Medical School

Insoo Hyun is Director of Research Ethics and a faculty member of the Center for Bioethics and senior lecturer on Global Health and Social Medicine at Harvard Medical School. He is also Professor of Bioethics and Philosophy at Case Western Reserve University School of Medicine. As a Fulbright Scholar and Hastings Center Fellow, Dr. Hyun's interests include ethical and policy issues in stem cell research and new biotechnologies.

Currently, Dr. Hyun is the Principal Investigator of a BRAIN Initiative-funded project exploring the ethical issues surrounding human brain organoid research, in collaboration with leading scientists at Harvard and Stanford. He is also a Co-Principal Investigator, along with colleagues at the Hastings Center, of an NIH grant identifying ways to improve the oversight of stem cell-based human-animal chimera research. Dr. Hyun has been involved for many years with the ISSCR (International Society for Stem Cell Research), for which he has helped draft all of the ISSCR’s international research guidelines and has served as their Chair of the Ethics and Public Policy Committee.

Dr. Hyun received his BA and MA in Philosophy with Honors in Ethics in Society from Stanford University and his PhD in Philosophy from Brown University. He has been interviewed frequently on National Public Radio and has served on national commissions for the Institute of Medicine and the National Academy of Sciences in Washington D.C. Dr. Hyun is a regular contributor to Nature, Science, Cell Stem Cell, The Hastings Center Report, among many other journals. His book Bioethics and the Future of Stem Cell Research was published by Cambridge University Press in 2013. He was recently named one of Cleveland’s Most Interesting People of 2019.

Publications View
Moonshots and Other Metaphors: The BRAIN Initiative.
Authors: Authors: Hyun I.
AJOB Neurosci
View full abstract on Pubmed
Ethical issues related to brain organoid research.
Authors: Authors: Hyun I, Scharf-Deering JC, Lunshof JE.
Brain Res
View full abstract on Pubmed
Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells.
Authors: Authors: Hyun I, Munsie M, Pera MF, Rivron NC, Rossant J.
Stem Cell Reports
View full abstract on Pubmed
Ethical considerations for human-animal neurological chimera research: mouse models and beyond.
Authors: Authors: Hyun I.
EMBO J
View full abstract on Pubmed
Informed Consent Issues for Cell Donors.
Authors: Authors: Hyun I.
Methods Mol Biol
View full abstract on Pubmed
Ethical Standards for Chimera Research Oversight.
Authors: Authors: Hyun I.
Methods Mol Biol
View full abstract on Pubmed
Debate ethics of embryo models from stem cells.
Authors: Authors: Rivron N, Pera M, Rossant J, Martinez Arias A, Zernicka-Goetz M, Fu J, van den Brink S, Bredenoord A, Dondorp W, de Wert G, Hyun I, Munsie M, Isasi R.
Nature
View full abstract on Pubmed
Erratum: Revisiting the Warnock rule.
Authors: Authors: Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L.
Nat Biotechnol
View full abstract on Pubmed
Engineering Ethics and Self-Organizing Models of Human Development: Opportunities and Challenges.
Authors: Authors: Hyun I.
Cell Stem Cell
View full abstract on Pubmed
Revisiting the Warnock rule.
Authors: Authors: Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L.
Nat Biotechnol
View full abstract on Pubmed